(Sung to the tune of "It's A Small World")
Verse:
There are just four bases in DNA.
There is G and T, and there's C and A.
And their sequence in genes
Forms our guts, lungs, and spleens
From our genome after all.
Chorus:
It's your genome after all,
It's our genome after all,
It's our genome after all
We've great gobs of genes.
Verse:
If your ACA turns to ACT
There's a world of problems
For you and me.
For the bases won't hold
And the protein won't fold
From your genome after all.
Chorus.
Verse:
While Cerberus may act to form our pates,
Chordin helps determine our neural plates.
Cause like in days of yore
It binds BMP4
From our genome after all.
(Add your own verses)
(To the tune of "Flintstones")
Histones!
Meet the Histones!
They're a basic protein family.
There are
Just four subtypes.
They're conserved evolutionarily.
Two each
Of each histone
Do their thing.
Forming
Just like beads upon a string.
H1
Binds the complex.
And it inhibits new transcription
And the creation
Of new mRNA.
Tune: YMCA
Student!
I was once in your shoes;
Got no staining
On my Coomassie Blues,
All my training
Was just paying my dues;
I could not get good data.
Then, someone
Said: Persulfate wonit do
And the Lowryis
Should be flushed down the loo.
They smell flowery,
But they will not get you
Any answers;
So study the
M-R-N-A
(yes, we study the)
M-R-N-A
It comes straight from the gene,
It can make a protein,
Itis the code that connects
The whole cellular machine!
Then I
Got the data galore,
Got new answers,
With each gel that I pour;
With enhancers,
I can even get more.
And I churn
Out the papers.
So student,
If your work has been slowed,
Skip the protein
And go straight for the code.
Do in situs
On a fly, mouse, or toad.
Get respect
When you study the
M-R-N-A.
(Study the)
M-R-N-A.
It can run on a gel,
And it blots really well.
Itis the way that you get
Your next paper in Cell.
M-R-N-A.
M-R-N-A.
M-R-N-A
M-R-N-A......